Pirimiphos is a trade name, generic name for compound dexamethasone acetate cream, anal itching patients use Pirimiphos more itchy may be hormone dependence, and did not play a therapeutic effect on the cause of the disease, resulting in itching and aggravation of repeated. Patients with anal itching are often caused by anorectal diseases or pathogenic infections, generally take hemorrhoidal ointment, surgery, anti-infective and anti-allergic drugs and other treatments, such as Ma Yinglong hemorrhoidal cream, acacia pills, amoxicillin, loratadine and other medications. The composition of compound dexamethasone acetate cream is mainly dexamethasone, mometasone and other hormones, which can’t play a therapeutic role for the cause of the disease, and therefore will cause itching to repeat and aggravate. It is recommended that patients go to the anorectal department in time, after the cause of the disease is clear, according to the cause of the disease can follow the doctor’s instructions to use local medicine or oral treatment with medication, if it is caused by anal and intestinal diseases can be considered for surgical treatment, to avoid their own blind use of medication, resulting in adverse reactions.