Causes of nighttime sleep heart fossa pain, i.e. chest pain, have more etiologies, mainly including coronary angina, pneumonia, pericarditis and other diseases. The degree of ordinary pain is relatively mild and generally tolerable, but if the following four conditions occur, those in serious condition need to consult a doctor as soon as possible: 1, acute myocardial infarction, for persistent chest pain, lasting for more than 30 minutes in most cases, rest or nitroglycerin can not be relieved, can be accompanied by irritability, sweating, fear or a sense of near death; 2, acute pulmonary embolism, mainly manifested as sudden chest pain accompanied by dyspnea, and can appear choking; 3, tension pneumothorax, most of which will have obvious triggers, such as coughing, and the patient can show chest pain with dyspnea on one side; 4, aortic coarctation, which shows persistent tear-like chest pain, can be accompanied by a drop in blood pressure, unequal blood pressure on both sides. The above four conditions are high-risk chest pain, and the mortality rate of patients is relatively high, so we must pay more attention to them.