Gout-induced knee pain may be associated with gouty attacks, which are often treated with medications in the clinic, including colchicine, non-steroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, and so on. 1. Colchicine: Colchicine in small doses has obvious efficacy in gout-induced arthritis, which can relieve pain to a certain extent and have fewer adverse effects. 2. Non-steroidal anti-inflammatory drugs: it has obvious efficacy on acute gouty arthritis and obvious effect on pain relief, but it should be prohibited for patients with peptic ulcer and active bleeding, and should be alert to the adverse effects of gastrointestinal tract and cardiovascular system. 3. Glucocorticoid: for the above two drugs are contraindicated or ineffective patients, can effectively inhibit pain, divided into oral and joint cavity injection of two routes of administration, should be reasonable choice under the guidance of the doctor. Gout patients are advised to go to the rheumatology and immunology departments of regular hospitals for detailed consultation and standardized diagnosis and treatment according to the doctor’s instructions. The medication should be used under the guidance of a doctor, and should not be used on its own.