Life is always full of ups and downs, and accidents always visit suddenly, which can have a great impact on people’s healthy life, such as sudden traffic accidents, falling objects and so on, which can lead to the occurrence of traumatic brain injury. And after the occurrence of serious traumatic brain injury, many of them need timely surgical treatment and handling to save the patient’s life. What is skull loss after trauma surgery? This is mainly because the traumatic brain injury leads to intracranial hematoma, and some patients also have intracranial hypertension, so they have to perform large bone flap decompression, and after the decompression of the bone flap, the removed bone flap will not be put back, which will lead to the cranial defect. Cranial defects should also be taken seriously, long-term cranial defects without treatment will have a certain impact on the patient’s health and psychology, and if an accident occurs again and accidentally injures the intracranial tissues, it will even cause life-threatening. Therefore, cranial defects should not be taken seriously, and patients with defects larger than 3 cm and eligible for surgery should have cranial repair surgery before it is too late. This is a routine surgery in neurosurgery with high safety, but in order to improve the success rate of the surgery, the choice of repair material is of paramount importance. Currently, many hospitals widely use titanium mesh material, which is a metal material and cheap, but it also has some shortcomings, such as a high chance of postoperative infection, affecting postoperative medical examination, risk of material exposure, etc.