Increased density of suprapatellar bursa can be treated by rest, avoiding weight bearing and excessive knee activities, hot compresses, physiotherapy, Yunnan Baiyao aerosol, external fixation with a brace, and surgery. The suprapatellar bursa is the largest mucus sac in the knee joint, and the increased density of the suprapatellar bursa indicates that there is fluid accumulation. The suprapatellar bursa can be treated by resting in bed, avoiding weight-bearing labor and excessive activities of the knee joint to reduce the abrasion of the knee joint and the production of fluid. Treatment can be given hot compresses, physiotherapy, Yunnan Baiyao aerosol to promote blood circulation and fluid absorption, if necessary, with the use of external fixation support. Surgery can be given when conservative treatment is ineffective. At the same time, the quadriceps muscle training should be done to increase the stability of the joint, so as to avoid producing more synovial fluid. If a suprapatellar bursa effusion is diagnosed, early and standardized treatment is recommended to minimize the adverse effects of the disease. Medications and treatments should be administered under a doctor’s supervision, not self-medication.