Peroneal myoatrophy, also known as Charcot-Marie-Tooth disease (CMT), is the most common group of familial peripheral neuropathies, accounting for approximately 90% of all inherited neuropathies. The common features of this group of diseases are childhood or adolescent onset, chronic progressive peroneal muscle atrophy, relatively symmetrical symptoms and signs, and a family history in most patients. Because the main clinical feature is peroneal muscle atrophy, it is also known as peroneal myoatrophy. The symmetrical atrophy of the peroneal muscle gradually progresses upward is the clinical symptom of the disorder. So, how to prevent the progressive development of symmetric atrophy of the peroneal muscle? The following is a brief introduction: this disease is a group of hereditary diseases, the only effective prevention method is to perform prenatal genetic diagnosis. Genetic diagnosis is used to determine the genotype of the pre-documented person, and fetal genotype is analyzed with fetal chorion, amniotic fluid or umbilical cord blood to determine prenatal diagnosis and terminate the pregnancy. Prevention of genetic diseases in the next generation begins with the selection of a spouse and marriage in the current generation. If health conditions are ignored in the selection of a spouse and a person with severe schizophrenia or leprosy is married, the next generation will have a significantly increased chance of developing a genetic disease. Those who suffer from dominant genetic diseases, such as chondrodysplasia, tuberous sclerosis and other severe deformities and mental retardation, should be sterilized before getting married. Secondly, if I suffer from a general genetic disease, I should avoid marrying someone who suffers from the same genetic disease. Such as primary hypertension, atherosclerosis, diabetes, congenital heart disease, myasthenia gravis, spina bifida, cleft lip, congenital hip dislocation, congenital asthma, congenital deafness and high myopia, etc. Do not marry each other between patients. In addition, patients who are suffering from virulent hepatitis, tuberculosis, venereal disease and some other serious organic diseases, should not be married.