Swelling of the head of the penis may be caused by acute injury, prepuce glans, allergies and other factors, mainly for drug treatment, the cause of the disease is different, the medication is not the same. 1. Acute injury: such as excessive pressure or external blows, in the acute stage, cold compresses can be applied, in the recovery period can be hot compresses, accelerate blood circulation, promote swelling subside, accompanied by pain symptoms, can be oral ibuprofen and other anti-inflammatory analgesic drugs to improve. 2. Foreskin glans: for bacterial infection caused by glans, can be used externally with erythromycin ointment, mupirocin ointment and other medications, there is a fungal infection, the need to use clotrimazole ointment, terbinafine ointment and other medications. 3. Allergy: when there are allergic factors, can also make the penis head swelling, can use tacrolimus ointment, glycerite lotion and other drugs for treatment, but also oral anti-allergy drugs, such as cetirizine and loratadine. In the process of treatment must follow the doctor’s guidance, safe and reasonable use of medication treatment, do not indiscriminate use of drugs.