Cranial defects will cause what harm? The current life of cranial defects in the population is gradually increasing, cranial defects are mostly due to open craniocerebral injury or firearm penetrating injury, some patients are due to surgical decompression or diseased cranial resection and residual bone defects. After the cranial bone defect should be timely to the regular hospital for cranial bone repair. What are the hazards caused by cranial defects? More than 3cm in diameter defects, especially in the frontal part of the defects that impede the beauty and safety, often have this or that symptom, such as dizziness, headache, local tenderness, irritability, restlessness and other manifestations; or the patient of the defective area of the throbbing, bulging, collapsing the storage of the fear of the sun, fear of vibration and even fear of the sound of the noises, often have poor self-control, attention is not easy to focus and memory loss; or depression, tiredness, and low self-esteem; or depression, tiredness and low self-esteem; and the lack of speech and low self-esteem; and the lack of self-control, attention is not easy to focus on and memory loss; or melancholy, fatigue, and low self-esteem, Or there are depression, fatigue, reticence and low self-esteem; or due to a large area of skull loss caused by the patient’s skull serious deformity, directly affecting the physiological balance of intracranial pressure, collapsed when standing upright, lying down when the expansion, concave in the morning, convex at night; or due to the atmospheric pressure directly through the defective area of the role of the brain tissues, which will inevitably lead to localized cerebral atrophy, aggravate the symptoms of cerebral impairment, and, at the same time, the ventricle on the side of the brain to the defective area of the expansion of dilatation or deformation. Therefore, the cranial bone repair surgery as soon as possible, the Civil Aeronautics General Hospital Department of Neurosurgery cranial bone repair material is selected polyether ether ketone peek material, the material has been recognized by many patients with cranial bone defects, cranial bone defects patients preferred cranial bone repair material. Cranial bone repair experts said that in order to restore the airtightness of the cranial cavity, maintain physiological intracranial pressure stability, reduce the cranial defect syndrome, the diameter of the cranial defect in more than 3 centimeters, no muscle coverage, no contraindications should be cranial bone repair, the operation time is generally selected in the craniotomy after three months. It is also very important to choose materials for cranial bone repair to reduce infection. Neurosurgeons use the new PEEK material for cranial bone repair, PEEK (polyether ether ketone) has high temperature resistance, corrosion resistance, strong, but also good toughness, does not affect the postoperative review and many other advantages.PEEK material shaping is generally used in the 3D printing technology as a whole shaping melting casting, so it can be personalized according to the patient’s cranial defects in the part of the situation of perfect shaping. Moreover, PEEK can significantly reduce the rate of subcutaneous fluid accumulation and subcutaneous infection after surgery.