The flesh of the tooth is swollen and painful, there may be gingivitis, wisdom teeth pericoronitis and other causes of gum swelling and pain, you can take sensitive antibiotics, as well as anti-inflammatory analgesic drugs, while targeted treatment. If it is pulpitis, apical periapical inflammation, generally need to carry out root canal treatment, more do not need to take drugs. 1. Gingivitis: Periodontal treatment is required, together with the following medications if necessary. (1) Sensitive antibiotics: periodontitis may be anaerobic bacteria or other bacterial infections, you can take metronidazole, tinidazole, cefadroxil, roxithromycin and other antibiotics for anti-infection treatment. (2) Anti-inflammatory and analgesic drugs: In case of severe pain, you can take anti-inflammatory and analgesic drugs such as ibuprofen, celecoxib and acetaminophen to relieve the symptoms. But the main need to carry out periodontal scaling and other periodontal sequence treatment. 2. Endodontitis: Endodontitis caused by tooth decay should be treated with root canal therapy. 3. Periapical inflammation: If there is periapical inflammation, root canal treatment should be carried out in time. 4. Wisdom tooth pericoronitis: local rinsing and medication is needed, and if it meets the indications for extraction, it is recommended to extract it in time. In the anti-inflammatory treatment, can use the above antibacterial drugs pain medication. Swelling and pain in the flesh of the tooth, it is recommended to go to the hospital for examination in a timely manner, and follow the doctor’s instructions for treatment and medication.