Vasodilator drugs are crucial in the treatment of heart failure, especially in patients with acute heart failure, and the main types of drugs can be nitroglycerin or sodium nitroprusside, which can be used as long as the blood pressure is stabilized. The main pharmacological basis is to reduce the preload and afterload of the heart by dilating the arteries and veins, for example, by dilating the veins to reduce the blood return to the heart, and by dilating the arteries to reduce the pressure of the heart in the process of ejection of blood, so that the total load of the heart to reduce the work of the heart through the two mechanisms, so that the symptoms of patients with heart failure can be improved, and the symptoms of heart failure corrected as soon as possible. In addition to the application of vasodilator drugs, like cardiotonic, diuretic need to be applied, and some drugs to improve the prognosis of heart failure, such as beta-blockers should also be added as early as possible.