Axillary lymphoma refers to lymphoma invading the axillary lymph nodes, which may not have typical clinical manifestations in the early stage, and is mostly characterized by enlargement of superficial axillary lymph nodes. Lymphoma is a common hematologic malignancy that originates from lymphatic tissues. If lymphoma invades axillary lymph nodes, most patients may not have obvious discomfort symptoms in the early stage, and a small number of patients may have the manifestation of axillary superficial lymph node enlargement. And lymph node enlargement caused by lymphoma is usually painless enlargement, so it is not accompanied by shoulder joint pain. When the disease further progresses and the tumor invades the nerves, shoulder joint pain and numbness of upper limbs may occur. If the disease further progresses and the tumor spreads to the whole body, systemic symptoms may appear, such as fever, self-conscious general weakness, emaciation and so on. If there are painless enlargement of axillary superficial lymph nodes, unexplained fever, emaciation and other symptoms, we should be alert to lymphoma. It is recommended to go to regular hospitals for consultation in time, and follow the opinion of specialists for clear diagnosis and standardized diagnosis and treatment.