Only pleural metastasis of lung cancer cannot be treated surgically in most cases, because when pleural metastasis occurs, it usually indicates that the patient’s condition is at an advanced stage and the chance of surgical cure is not great, so it is recommended to treat it by radiotherapy and chemotherapy to prolong the survival period. 1. Radiotherapy: Radiotherapy is suitable for patients with advanced stage of limitation or those who cannot be operated due to old age or cardiopulmonary insufficiency, etc. It can be divided into radical, palliative, adjuvant, neoadjuvant and prophylactic types. 2. Chemotherapy: Patients can kill cancer cells through oral intake or injection of chemical drugs, so as to achieve the purpose of treatment. Chemotherapy is one of the main treatment methods for this disease, and more than 90% of patients need to receive this treatment to relieve symptoms, improve quality of life and prolong life cycle. 3. Others: For patients with advanced lung cancer, immunotherapy can also be applied, and if there are targeted genes in genetic examination, targeted drug therapy can be applied. If lung cancer is treated with surgery at early stage, it is usually curable, but for advanced stage patients with pleural metastasis, it is recommended to choose other methods of treatment and do good management of daily diet and exercise, so as to control the development of the disease as far as possible.