What’s a low-grade tubular adenoma grade 2?

Low-grade tubular adenoma grade 2 refers to moderately differentiated intestinal polyps, which are precancerous and have a certain chance of malignancy. Clinically, tubular adenomas are classified as high-grade, intermediate-grade and low-grade tubular adenomas, of which low-grade tubular adenomas are what we call intestinal polyps, and low-grade tubular adenomas grade 2 means that there is atypical hyperplasia of intestinal polyps. Histologically, adenomas are classified into three grades, with grade 1 being highly differentiated, grade 2 being moderately differentiated, and grade 3 being undifferentiated. If it is grade 1, the cells are similar to normal cells; if it is grade 3, the cells are more different from normal cells and have a higher risk of becoming cancerous, generally referred to as precancerous; and if it is grade 2, it is somewhere in between. Patients diagnosed with low-grade tubular adenoma grade 2 need to have it removed surgically as soon as possible. If not removed, the adenoma may gradually increase in size, and if accompanied by rupture and infection, symptoms such as abdominal pain, bloating and blood in the stool may occur. Moreover, as time progresses, the adenoma may become cancerous, and once cancerous, the prognosis is often poor.