There is no evidence that eating ayahuasca cake can get rid of melasma. Melasma is usually treated by photoelectric treatment and chemical peeling, topical application of hydroquinone and its derivatives, and retinoids. Melasma is a chronic, acquired disease causing increased pigmentation of facial skin, clinically manifested as symmetrical brown patches of different shades and fuzzy boundaries on the skin of cheeks, forehead and other parts of the body. The following treatments are commonly used for melasma 1. Medication: Melasma can be treated with aminomethylcyclic acid, glycyrrhizin, vitamin C, vitamin E, glutathione and other medicines as prescribed by doctors during the active period; topical medicines can be hydroquinone and its derivatives, retinoids, azelaic acid and so on; 2. Other treatments: chemical peeling with fruit acid and photoelectric treatment such as Q laser and picosecond laser can be used in the stabilization period. It is recommended to go to regular medical institutions to follow the doctor’s instructions to standardize the treatment, do not self-medication.