Patients with Turner syndrome can undergo IVF, but the success rate is not high and depends on their fertility.
Turner syndrome, also known as congenital ovarian hypoplasia, is a group of disorders due to sex chromosome abnormalities. While normal women have 2 X chromosomes, patients with classical Turner syndrome have only 1 X chromosome and are infertile.
Incomplete Turner syndrome, also known as chimeric Turner syndrome, preserves fertility in some patients. It manifests as a result of complete or partial deletion or structural abnormality of the X chromosome. Due to the abnormal karyotype of the chromosomes, there may be a lack of development of secondary sexual characteristics and abnormal ovarian development.
IVF involves retrieving mature follicles from the ovaries, fertilizing them with sperm outside the body and then planting them in the uterus, followed by conception and delivery. For the small percentage of women who retain their fertility, pregnancy can be achieved through assisted reproductive technology. However, as Turner syndrome is often combined with multiple complications, detailed assessment of the associated complications or potential complications should be carefully considered before pregnancy.