Severe anemia is mainly manifested by dizziness, pallor, fatigue, palpitations (rapid heartbeat, often accompanied by panic), and shortness of breath after activities, of which fatigue is the most common. It also manifests as decreased physical strength, developmental delay, mental retardation, inattention, irritability, irritability or indifference, xenophagia, etc.; pale skin and mucous membranes, dry hair, flat nails, lack of luster, and easy to chip, anti-nail, and in severe cases, it can cause splenomegaly. Some patients with severe anemia can also cause edema. Therefore, there is no direct link between weight gain and severe anemia. If the patient shows weight gain, it may be due to splenomegaly or edema, but not obesity. If the patient has severe anemia, it is recommended to go to the hospital in a timely manner, under the guidance of the physician for early and regular treatment.