The medication for multiple cavernous infarcts is taken under doctor’s supervision according to the principles of obtaining cerebral blood flow to brain tissues, reducing the degree of cerebral ischemia, protecting nerve cells and their functions, and preventing the expansion of thrombus and the occurrence of new thrombus. They include drugs to improve cerebral circulation, anticoagulants, preventive cerebrovascular drugs and neuroprotective drugs. 1. Drugs to improve cerebral circulation: calcium antagonists, commonly used flunarizine, nimodipine, etc., butylphthalide, butylcholestyramine and so on. 2. Anticoagulants: new oral anticoagulants include apixaban, dabigatran and rivaroxaban. Compared with warfarin, the main advantages of new oral anticoagulants are less risk of bleeding, no need to test coagulation function, and fewer interactions with food and other drugs. 3. Drugs for prevention of cerebrovascular disease: antiplatelet aggregation drugs, aspirin, clopidogrel, and so on. 4. Neuroprotective drugs: methylcobalamin, cytarabine sodium, etc. to nourish the nerves. It is recommended that patients with multiple cavernous infarcts consult a doctor in time and take medication under the doctor’s guidance to avoid adverse reactions.