The time of blood glucose drop after treatment with different medications varies in diabetic patients, and the specific time varies from person to person. Diabetic patients usually first carry out non-pharmacological treatment to control blood sugar, such as diet control, moderate exercise, weight loss, etc.; if the control is not good, oral hypoglycemic drug treatment is needed; if it is still uncontrollable, insulin-like drugs need to be injected. As different oral hypoglycemic drugs have different mechanisms of action, the onset of action is also different, and even the time of taking the drug and the side effects of the drug are also different. For example, glucosidase inhibitors need to be taken after the first bite of food to lower postprandial blood glucose, and non-sulfonylurea insulin pro-secretory agents are taken 15 minutes before a meal to have a fast effect and lower postprandial blood glucose. Different patients use different glucose-lowering drugs, and even some patients use combined drugs to lower blood glucose, resulting in different glucose-lowering times. Therefore, diabetic patients should go to the endocrinology department of the hospital and take drugs consistently, reasonably and regularly under the guidance of doctors.