The gallbladder absorbs, secretes, and moves, thus functioning to concentrate, store, and excrete bile. First of all, the mucous membrane of the gallbladder can absorb water and electrolytes in the bile, and can concentrate the bile by more than 5-10 times and store it in the gallbladder. Concentrated bile plays a very important role in the digestion of food, especially fatty foods. Secondly, although the secretion of bile is continuous, the discharge of bile occurs intermittently with feeding, mainly through the contraction of the smooth muscle of the gallbladder and the relaxation of the sphincter of Oddi, which is regulated by both the nervous system and humoral factors. In addition, the mucosa of the gallbladder secretes about 20 ml of mucus material per day, mainly mucin, which lubricates and protects the mucosa of the gallbladder. After gallbladder removal, the common bile duct will be compensatory enlargement, wall thickening, mucosal gland hypertrophy increased, so that the bile secreted by the liver and then through the bile duct can get a certain degree of concentration, so as to play a part of the replacement of the gallbladder’s function.