Tadalafil and sildenafil can not be taken at the same time, they belong to the same class of drugs, choose one can. Tadalafil and sildenafil are both phosphodiesterase inhibitors of type 5, the first-line drugs for the treatment of erectile dysfunction in men, they belong to the same class of drugs, the mechanism of action is the same, and taking them at the same time will not increase the effect of the action of the effect of the side effects may also occur, according to the doctor’s instructions to choose a drug can be. Taking tadalafil and sildenafil may cause headache, dizziness, indigestion, nasal mucous membrane congestion and other adverse reactions. Neither drug should be taken with nitrate drugs (such as nitroglycerin, etc.), which may cause severe hypotension. If you are suffering from erectile dysfunction, it is recommended to go to a regular hospital to actively seek medical treatment, and choose the appropriate medication under the guidance of a professional doctor.