Compared with clindamycin, cephalosporin is better, cephalosporin belongs to the β-lactam antibiotics, which has a wide range of antibacterial and few side effects, and is widely used in clinical practice. Cephalosporin is used to treat respiratory infections, genitourinary infections, central nervous system infections, skin and soft tissue infections and other diseases caused by sensitive bacteria. The drug is well absorbed orally, mainly metabolized in the liver, and most of it is excreted through the kidneys in the form of urine. The main adverse reaction of this drug is allergic reaction, so patients with cephalosporin allergy should be prohibited, which can be manifested as skin rash and itching and other symptoms, in addition to gastrointestinal reactions, the patient can have nausea, vomiting, abdominal pain, diarrhea and other clinical symptoms, after stopping the drug, the symptoms will gradually disappear.