Patients who experience difficulty in breathing while sleeping at night may be related to asthma, bronchitis, heart failure and other diseases, and patients may find relief through general treatment and medication. 1. Asthma: Patients may experience symptoms such as coughing, wheezing and difficulty breathing after exposure to allergens, which are usually more severe in the morning and evening. Asthma patients should avoid contact with allergens or other non-specific stimuli that cause asthma attacks, and if necessary, patients can be treated with oxygen. Asthma patients can be treated with glucocorticosteroids such as beclomethasone, budesonide, prednisone, etc., as well as terbutaline, montelukast, zalustat, etc., under the guidance of a doctor. Patients can also be treated surgically with bronchial thermoplasty if necessary. 2. Bronchitis: patients may manifest cough, cough sputum, and when the symptoms are severe, dyspnea may also occur, unable to come up for air. Patients should rest properly, avoid exertion, drink plenty of water, quit smoking, and avoid inhaling harmful gases and other harmful particles. Patients can take antibiotic drugs, such as roxithromycin, amoxicillin, cefuroxime, etc.; asthma medicines, such as aminophylline and other drugs for treatment under the guidance of doctors. 3. Heart failure: patients may manifest cough, cough pink foamy sputum, dyspnea, often manifested as sitting breathing. Heart failure patients should choose semi-recumbent position or sitting position, legs down, in order to reduce venous return, usually patients should limit heavy physical labor and strenuous exercise. Patients can be treated with diuretics, such as furosemide, hydrochlorothiazide, spironolactone, etc.; vasodilator drugs, such as sodium nitroprusside, nitroglycerin, isosorbide dinitrate and other drugs under the guidance of the doctor. In addition, pneumonia, tuberculosis, carbon monoxide poisoning, acute cerebral hemorrhage and other diseases may also cause nocturnal dyspnea, it is recommended that the patient consult a doctor for examination in a timely manner, to identify the cause of the disease and then carry out targeted treatment. The above drugs should be used under the guidance of a physician.