Hypertension caused by adrenal enlargement is considered to be primary aldosteronism and other diseases, which can usually be cured, and surgery is generally preferred, with medication as an adjunctive treatment. Hypertension due to enlarged adrenal glands is usually considered secondary hypertension and can be treated by surgically removing the enlarged portion of the adrenal gland. The enlarged portion of the adrenal gland may cause an increase in aldosterone and other hydrocorticoid hormones, and too much aldosterone in the body can cause sodium retention, leading to an increase in blood pressure. If the surgery is not effective, the use of antihypertensive drugs to assist in the treatment, can choose aldosterone antagonist spironolactone and long-acting calcium channel blocker amlodipine and other drugs for treatment. It is recommended that patients go to regular hospitals, specific drugs need to be used under the guidance of the doctor.