I often meet patients with first-onset diabetes in the outpatient clinic. Many patients with first-onset diabetes cannot accept that they have diabetes, so they are very reluctant to take medication and insulin treatment, and they are even more reluctant to be hospitalized. When I meet these patients, especially when they are sad and overwhelmed, I deeply feel the importance of patient education. It also prompted me to write this article, hoping to give some help to patients. How should a patient with first-onset diabetes be treated? What is best for the patient? Should they be hospitalized or not? Each patient’s situation is different, so our choices are different. When a patient has just discovered that he or she has diabetes and the glycated hemoglobin is below 9% (glycated hemoglobin reflects the average blood glucose level over the past 2-4 months), for patients with type 2 diabetes, this is the time to choose oral hypoglycemic drug therapy. The choice of specific medication requires blood glucose measurement and is determined by fasting and postprandial glucose. If glycated hemoglobin is greater than 9%, this is when we recommend insulin intensive therapy. Regarding the application of insulin, there are many patients who are afraid when they hear of insulin and worry about long-term dependence. Here, we explain that whether insulin is dependent or not depends on the patient’s diabetes type. This article focuses on type 2 diabetic patients. type 2 diabetic patients can switch to oral medication at any time after applying insulin therapy. Why should patients with initial onset be treated with insulin? The general idea is that it allows for better recovery and long-term clinical remission of beta cell function in our newly diagnosed type 2 diabetic patients. What do the pancreatic beta cells do? They secrete insulin, and what does insulin do? Insulin is for lowering blood sugar. What does long-term clinical remission mean? It means that after a period of intensive insulin treatment, blood sugar can be controlled at normal level without insulin or medication. Of course, the clinical situation of patients is diverse, and some patients may not achieve the best effect of no insulin and no medication after intensification, but after intensification, the pancreatic islet cells are restored to a certain extent, and less medication may be needed at this time. Do patients with first-episode disease need to be hospitalized? Hospitalization does not mean that your disease is heavy. Rather, it means that we have a comprehensive understanding of our disease, and every day the doctor will talk about diabetes. These are important for patients, especially those who have a first episode. How should we eat? How to be active? How to review? What should we do after we leave the hospital? How to prevent complications? All of these things can be helped during hospitalization through communication with the doctor. The second purpose of hospitalization is to have a comprehensive understanding of our body and how it is doing. One can keep a bottom for future comparison, in addition, can also be early detection of their health problems early treatment. The third purpose of hospitalization is to develop a glucose-lowering plan that is suitable for us, whether we have type 1, type 2 or other types of diabetes. We will monitor our blood glucose every day while we are in the hospital, so that the glucose-lowering plan that is made according to our blood glucose level may be more suitable for you.