Mild intestinalization is usually not important. Intestinalization refers to intestinal epithelial hyperplasia, which is a transformation process of gastric mucosa from normal to intestinal epithelium, and gastric mucosal epithelium is transformed into small or large intestinal mucosa. At present, since it is only mild intestinalization, it is generally not serious, but it still needs timely treatment, or else it may be transformed into gastric cancer. The occurrence of mild intestinalization usually requires a test for Helicobacter pylori, and if the diagnosis is confirmed after Helicobacter pylori, timely quadruple therapy is required, i.e., a proton pump inhibitor, a bismuth agent and two antibiotic drugs, such as omeprazole, bismuth potassium citrate, metronidazole, amoxicillin, and so on. If H. pylori infection does not occur, acid-suppressing drugs and mucosal protectants, such as omeprazole, rabeprazole, bismuth pectin, aluminum thiosulfate, etc., can be taken alone. All of the above drugs need to be taken in accordance with the doctor’s instructions, and patients should not use the drugs at will.