1. About 20% of patients with active TB can have no clinical symptoms or only mild symptoms. 2. A few patients may have tuberculous rheumatism, which manifests as joint pain or even deformity. 3.Some patients may have tuberculosis hypersensitivity syndrome, such as nodular erythema or annular erythema intermittently appearing near large joints and vesicular conjunctivitis. 4.Females may show menstrual irregularities, and a few females show the triad of mouth, eyes and genitalia. 5.Children may have personality change, irritability, irritability, etc. 6.In immune compromised individuals (referring to patients with primary immunodeficiency diseases and those treated with radiotherapy and immunosuppressive therapy), the symptoms of TB are insidious or mild and may lack respiratory symptoms, atypical lung images, and negative immunological findings such as tuberculin test and TB antibody test. 7, can also be due to dysregulation of the immune defense mechanism with pathologically damaging metaplasia overload, can be sudden onset of high fever, rapid progression of lesions in a fulminant process, some cases of lung X-ray imaging and acute pneumonia difficult to distinguish, but diagnostic treatment is often ineffective or although effective but not ideal.