Patients in the anal use of antipyretic drugs, the main hazards are the following: First, anal antipyretic drugs are non-steroidal anti-inflammatory drugs, the effect of reducing fever is very good, but there will be a lot of sweating caused by a rapid drop in body temperature, if the use of drug dose is too large, sweating more sometimes appear deflated, or have hypotension, accelerated heart rate, reduced urine volume, if the situation is serious, there will be blurred vision, easy to appear Hypovolemic shock. Second, if the long-term use of non-steroidal anti-inflammatory drugs to reduce fever, may cause peptic ulcers, if not treated in a timely manner, the ulcer will expand after the appearance of upper gastrointestinal bleeding. In summary, in addition to the two hazards, the use of anal antipyretic drugs is also prone to damage to liver and kidney function.