Ambroxol and Doxophylline can be used together, but if the dosage forms used are both injectable, the two medications should not be mixed together and need to be titrated separately. Ambroxol is a mucolytic medication, which can be used to improve the treatment of various acute and chronic respiratory diseases caused by thick sputum and coughing sputum difficulty. Dosophylline, on the other hand, is a bronchodilator medication that can be used to treat bronchial asthma, wheezing chronic bronchitis, and other breathing difficulties caused by bronchospasm. It is possible to combine Ambroxol and Doxophylline in order to treat related conditions. However, if both are used by injection, the two medications should not be mixed together and should be injected separately, as this can lead to free precipitation of Ambroxol. Adverse reactions: A small number of people have experienced mild gastrointestinal discomfort as well as allergic reactions after using Ambroxol. And a small number of patients will experience abdominal discomfort, palpitations, nausea, vomiting, insomnia and other adverse reactions after the use of Doxophylline. Contraindications: Dosophylline is contraindicated in those who are allergic to Dosophylline and those with acute myocardial infarction. The drug should be contraindicated for those who are allergic to Ambroxol. Precautions: Ambroxol should be used with caution in cases of impaired bronchomotor function and in the presence of copious secretions. Doxophylline should not be taken with other xanthines and do not consume caffeinated beverages or foods while taking the medication. Individuals using either Ambroxol or Doxophylline, either alone or in combination, should do so in accordance with their doctor’s instructions.