Is frequent use of vasodilators harmful to blood vessels?

Frequent consumption of vasodilators is not harmful to blood vessels.
Vasodilators are commonly used as nitrate drugs, such as isosorbide nitrate and isosorbide mononitrate. When myocardial ischemia occurs, it works by dilating the coronary arteries, increasing the blood flow in the narrowed blood vessels, and improving myocardial blood supply, and it has the function of dilating blood vessels, and it does not have an adverse effect on the elasticity of the blood vessels or the endothelium.
The presence of plaque in the coronary arteries leads to narrowing of the blood vessels and obstruction of blood flow, resulting in distal myocardial ischemia and hypoxia, and symptoms occur, so it is generally recommended to give nitrate drugs to dilate the coronary blood vessels, and it is recommended to take them for a long period of time, and in the process of dilating the blood vessels, it increases blood flow through the stenosis and improves myocardial blood supply, and it does not have any significant harm to the elasticity of the vessels or the endothelium of the blood vessels.
Long-term oral vasodilators should be followed up with regular reviews in the cardiology clinic.