Dizziness while sleeping and getting up may be caused by cervical spondylosis, otolithiasis, postural hypotension and other factors. 1. Cervical spondylosis: prolonged work at desk may induce cervical spondylosis, causing compression of the vertebral artery. When sleeping and waking up, due to the change of head position, the vertebral artery may be aggravated by the compression, which affects the blood supply and oxygen supply to the brain, and will cause dizziness. 2. Otolithiasis: It may be related to head trauma, surgery and other factors. When sleeping and getting up at night, otoliths may fall off, which will cause dizziness, and the duration of dizziness is usually not more than 60 seconds, which may be accompanied by nausea and vomiting and other symptoms. 3. Postural hypotension: it may be related to the change of body position, when lying down and getting up, the amplitude is larger and the speed is faster, which may cause postural hypotension, and the symptoms of dizziness will appear. Prolonged dizziness while sleeping and getting up should be alerted to disease factors, it is recommended to carry out the appropriate examination and treatment.