Vulvar itching and odor need to first identify the cause of the disease and treat the cause. If the local inflammation caused by bacteria, trichomonas or fungi leads to vulvar itching and odor, antibiotics and antifungal drugs can be used under the guidance of a physician; if the cause is estrogen deficiency, then the use of contraindications can be ruled out after the reverse addition of estrogen drugs. 1. Antibiotics: For vulvar itching and odor caused by trichomonas vaginitis and bacterial vaginitis, antibiotics are usually used for treatment. Trichomonas vaginitis to systemic treatment, taking metronidazole or tinidazole, need to avoid sexual intercourse and breastfeeding during the drug. Bacterial vaginosis to anti-anaerobic treatment, including local use of metronidazole vaginal suppositories, clindamycin ointment and so on. 2. Anti-fungal drugs: for candidiasis caused by vulvar itching and odor, you can use fluconazole, clotrimazole and other anti-fungal drugs, and at the same time, use 2% to 4% of baking soda water sitz bath. 3. Estrogenic drugs: For patients with atrophic vaginitis, estrogen replacement therapy can be carried out by the physician’s assessment to exclude contraindications, including local application of estriol cream, oral tibolone tablets, etc., and the combination of bacterial infections can be clarified after the causative organisms and the rational use of antibiotic therapy. Vulvar itching and odor may also have other causes, it is recommended to go to the hospital in a timely manner to identify the cause of the disease for targeted treatment.