The treatment of stage Ia highly differentiated endometrial cancer is mainly based on surgery, and radiotherapy and other adjuvant treatment modalities can be integrated according to the situation. The treatment options of endometrial cancer usually need to be considered in conjunction with the patient’s age, pathologic type and molecular staging, and clinical stage. For endometrial cancer stage Ia, comprehensive staging surgery should be performed, and intraoperative abdominal washings should be sent for cytopathologic examination to take biopsy samples from suspicious areas. If the patients are not suitable for surgery, other treatment methods such as radiotherapy can be considered. Adjuvant treatments such as radiotherapy and chemotherapy can also be taken according to the condition after surgery. However, generally speaking, stage Ia hyperfractionation belongs to the low-risk group, and its chances of recurrence are relatively low, so adjuvant treatments are generally not needed. At the same time, it is necessary to pay attention to regular gynecological examination, ultrasound and other imaging examinations to assess the condition. It is recommended to seek timely and standardized diagnosis and treatment when necessary.