Positive ER and PR in endometrial cancer suggests the presence of estrogen and progesterone receptors on the tumor.
ER is also known as estrogen receptor and PR is also known as progesterone receptor in endometrial cancer tissues. Positive ER and PR in the immunohistochemistry program indicates that treatment with hormones is more effective.
The positive expression rate of ER and PR in endometrial cancer is related to the histologic grade, and the positive expression rate decreases with the increase of histologic grade, and the difference is significant.
The expression of ER and PR was related to clinical stage, myometrial infiltration, and extrauterine foci, and the difference was significant. The higher the degree of tumor differentiation, the higher the positive expression rate of ER and PR, and the worse the degree of tumor differentiation, the lower the positive rate of hormone receptor.
It is recommended that patients seek timely medical treatment and take appropriate treatment plan under the guidance of doctors.