Paget’s disease of the breast is a special type of breast cancer, also known as eczema-like breast cancer, which belongs to malignant tumors. Whether it can be cured or not is mainly decided according to the patient’s stage of the disease, treatment mode, and the patient’s physique, etc.; for the early stage patients who have a good physique, the treatment at an early stage is generally curable, but it can’t be generalized. 1. Staging: for patients with early Paget’s disease, the scope of early lesions is relatively limited, no distant metastases, early standardized treatment, such as radical surgery to remove the lesions, can achieve clinical cure; for the middle and late Paget’s disease, there are obvious metastases, the difficulty of the treatment is relatively greater, and it is usually not easy to cure. 2. Treatment: According to the specific condition of the patient, after early standardized treatment, there is a greater possibility of cure, such as breast cancer lesion excision and lymphatic cleansing surgery, clinical cure may be achieved. However, for breast cancer patients without early standardized treatment, their condition may further aggravate and develop into advanced stage, which is not easy to be cured; however, they can still control their condition well through radiotherapy, chemotherapy (such as 5-fluorouracil, cisplatin, etc.), and targeted drug (apatinib, etc.) treatment to slow down their life. 3. Physical fitness: For patients with better physical fitness, the resistance is stronger, and compared with patients with poor physical fitness, the possibility of cure is greater. Meanwhile, for breast cancer, molecular typing also determines the clinical prognosis. In conclusion, in eczema-like breast cancer, the ability to cure is influenced by a number of factors. It is recommended that patients with Paget’s disease should seek medical attention in a timely manner and receive standardized treatment from a medical professional.