If the vaginal opening does not close for a long time during menopause, it is considered to be caused by the relaxation of the pelvic floor muscles due to the decrease of estrogen level, which can be treated with estrogen supplementation and pelvic floor physiotherapy as prescribed by the doctor. 1. Supplementary estrogen: The vaginal opening does not close during menopause, which may be caused by the decrease of estrogen and the relaxation of pelvic floor muscles, and the symptoms are obvious, so you can go to the gynecology department of the regular hospital to take estrogen treatment under the guidance of the doctor, such as estradiol valerate. However, if the patient has breast disease and estrogen resistance disease, estrogen treatment cannot be applied. 2. Pelvic floor muscle physiotherapy: you can also do pelvic floor muscle training activities such as Kegel exercises, exercise pelvic floor muscle, improve symptoms; you can also carry out electrical stimulation, so that the muscle fast fibers to achieve the role of reflexive training, promote local blood circulation, increase muscle strength and elasticity, prompting the closure of the vaginal opening. Therefore, if you find that the menopausal vaginal opening does not fit for a long time, you need to go to the hospital in a timely manner, and the drug needs to be taken in accordance with the doctor’s instructions.