In case of persistent asthma, nursing care should relieve the patient’s nervousness and anxiety, monitor the patient’s vital signs, such as heart rate, blood pressure, oxygen saturation, etc., and administer oxygen at an appropriate concentration according to the patient’s condition, advise the patient to drink more water, assist the patient to pat the back to expel sputum, assist the patient to use nebulized inhalation therapy, observe the patient’s clinical symptoms, the degree of relief, and any adverse drug reactions, etc., and record the patient’s Observe the patient’s clinical symptoms, the degree of relief, and the absence of adverse drug reactions. If the patient has thick sputum, expectorant drugs should be given, and if necessary, nebulized inhalation treatment should be used. Supplementary fluids should be given to avoid thick sputum that cannot be easily coughed out, and anti-infective treatment should be strengthened when combined with respiratory tract infection. For critically ill patients with respiratory failure and mental and physical changes, early invasive ventilator assisted respiratory therapy should be given.