The possible causes of toe pain are lumbar disc herniation, peripheral neuropathy, gout, as follows: First, lumbar disc herniation: if the lumbar disc herniation, it will compress the nerves that innervate the lower limbs, so some patients will have toe pain in the early stage of the phenomenon. Second, peripheral neuropathy: if there is some peripheral neuropathy, especially refers to diabetic peripheral neuropathy, diabetic peripheral neuropathy can also appear in the early pain, numbness phenomenon. Third, gout: if there is gout, be alert, especially middle-aged and elderly friends or patients with high uric acid, often have toe pain, especially at night, which is the most common site of gout, then you need to take drugs such as ibuprofen or cilostro to reduce the inflammatory response.