Wrist pain may be caused by physiological factors such as overwork of the thumb and wrist, or it may be caused by certain diseases, such as tenosynovitis, triangular fibrocartilage complex injury. 1. Physiological factors: long-term overuse of the thumb and wrist, may cause damage to the interosseous muscle and other muscles, the symptoms of the thumb a move wrist pain, generally can be relieved after rest. 2. Tendovaginitis: prolonged keyboarding and other activities may cause excessive friction between tendons and tendon sheaths, resulting in tendovaginitis. The common symptoms are localized pain, activity limitation, etc., appearing small thumb a wrist pain. 3. Triangular fibrocartilage complex injury: the triangular fibrocartilage complex is located in the ulnar side of the wrist joint, the wrist may lead to injury after strenuous activities, sprains, manifested as localized pressure pain, wrist pain on the side of the little finger. If there is a thumb a wrist pain, it is recommended that the patient consult a doctor in a timely manner to identify the cause of the disease and carry out the appropriate treatment.