Chronic obstructive pulmonary disease is the abbreviation of chronic obstructive pulmonary disease, which is a chronic inflammatory disease of the airways. The treatment in the acute exacerbation period mainly includes the following aspects, 1. To clarify the cause of acute exacerbation and also to assess the severity of the disease. 2. To remove the triggering factors, such as the presence of bacterial infection, to choose the appropriate antibiotic treatment, for example, you can choose amoxicillin clavulanate potassium or cefaclor, cefuroxime and other antibiotic treatment. 3. To relieve the symptoms of chest tightness, shortness of breath and dyspnea. Use more bronchodilators, such as salbutamol sulfate and ipratropium bromide, etc. 4. Control chronic inflammation of the airways. For severe cases requiring hospitalization, systemic glucocorticoids, such as oral prednisone or intravenous methylprednisolone injection, can be used.5. Expectorant treatment, such as aminoglutethimide hydrochloride or acetylcysteine, is needed for those with more sputum.6. Actively treat complications, such as low-flow oxygen or non-invasive ventilator-assisted ventilation for those with respiratory failure.