Abnormal infertility of seminal tract is usually considered to be caused by congenital factors and acquired factors. 1. Congenital factors: such as congenital incomplete development of epididymis, usually due to chromosomal abnormalities and other factors, leading to abnormal seminal tract and infertility. It can be treated with drugs such as testosterone propionate and methyltestosterone under the guidance of doctors, and for patients with more serious conditions, surgery and other methods can be used for treatment. 2. Acquired factors: including surgical ligation, gonorrhea infection, etc. In daily life, patients do not pay attention to personal hygiene, or unclean sexual behavior, it is easy to lead to infection of gonorrhea, the emergence of spermatic duct abnormality, narrowing, infertility phenomenon. It needs to be treated with drugs such as ceftriaxone sodium and cefotaxime under doctor’s guidance. Patients should go to the hospital for examination in time to avoid delays and adverse reactions when the seminal tract abnormality and infertility occurs.