Whether hepatitis requires antiviral treatment in the presence of fatigue and poor appetite is mainly determined by the combination of hepatitis B virus DNA measurement and liver function measurement. If the value is not abnormal, no antiviral treatment is needed; if the value is obviously abnormal, antiviral treatment is needed. 1. Do not need antiviral treatment: after viral infection, symptoms of fatigue and poor appetite will appear, through the examination of hepatitis B virus DNA is negative, and there is no increase in gammaglutaminase status, so you can not need antiviral treatment first, adjust the diet and physical condition, and monitor the change of the condition. 2. Need antiviral treatment: abnormal indicators need antiviral treatment, including the following three cases: ① major triple yang: hepatitis B viral DNA value reaches more than 6 times of 10, and alanine aminotransferase is more than twice of the need for antiviral treatment. Minor triple positive: Hepatitis B virus DNA value reaches more than 5 times of 10, and ASTE is more than twice as much as antiviral treatment. (iii) Cirrhosis: Hepatitis B virus DNA positive all need antiviral. Clinical history of hepatitis, once diagnosed with active hepatitis B through various tests, need to be admitted to the hospital in a timely manner, under the guidance of the clinician for standardized treatment, to avoid delays in the condition.