Physical growth retardation and dysplasia are endemic features of Cretinism. Patients are short and disproportionate, with the lower part of the body shorter than the upper part, and skeletal development is delayed, manifested by late appearance of the nucleus pulposus and small growth. Endemic cretinism mental retardation is a syndrome that is a specific term for psychiatric disorders. The onset of the disease is before the age of 18, with an IQ below 70 and varying degrees of social adjustment difficulties. The psychiatric symptoms of Dictyostelium actually belong to mental retardation, and generally IQ less than 50 is classified as Cretinism, while 50-69 is classified as subclinical Cretinism. Intellectual backwardness is the main feature of Dictyostelium, severe cases are idiots, unable to take care of themselves; mild cases can work, but cannot engage in skilled labor; subclinical Cretinism (subcretinism) are difficult to graduate from elementary school. Mucinous type of cretinism is less mentally challenged than neurological type, showing slow thinking and slightly higher IQ than neurological type, but as far as mental retardation is concerned, there is no essential difference between the two types of cretinism. Bone nucleus appears late, the development of small patients dietary considerations: 1, supply enough protein: the amount of high-quality protein supplied per person per day should exceed at least 20 grams to maintain the balance of protein in the human body. Once the protein is reduced, it should be supplemented with the necessary amino acids and supplied with sufficient protein to improve the condition. Therefore, more eggs, dairy, meat and fish should be consumed, and attention should be paid to the complementarity of vegetable and animal proteins. 2, avoid using raw goiter substances: avoid cabbage, cabbage, rape, cassava, walnuts, etc., to avoid the occurrence of shin goiter. 3, limit fat and cholesterol-rich diet, such as fatty, fried food. 4, avoid smoking, alcohol. 5, avoid tobacco, alcohol, moldy, pickled food.