Enalapril maleate and metoprolol, can be combined when there is a drug indication. Enalapril maleate is a blood pressure-lowering drug, mainly used in the treatment of primary hypertension and other diseases; metoprolol is a β-adrenergic receptor blocker, which can be used in the treatment of hypertension, angina pectoris, myocardial infarction, arrhythmia and so on; when patients with hypertension are ineffective in the treatment of taking a single blood pressure-lowering drug, they can follow the doctor’s instructions to use the combination of the above two medications, so as to achieve the ideal effect of lowering blood pressure. Enalapril maleate is usually contraindicated for people with bilateral renal artery stenosis and those with severely impaired renal function. Dizziness, headache, nausea, leukopenia and other discomforts may occur during the process of medication; therefore, renal function and leukocyte count need to be monitored during the process of medication, and the medication needs to be used under the guidance of a doctor for the elderly, children and other special populations. Metoprolol is contraindicated for people with cardiogenic shock, sick sinus node syndrome, allergy to the components of the drug, and symptomatic bradycardia; thrombocytopenia, elevated aminotransferase, chest pain and other discomforts may also occur during the use of the drug, so it is necessary to pay attention to the monitoring of liver function, blood routine, etc.; for athletes, pregnant women and other special groups of people, the need to be guided by a doctor to use the drug. If you need to use drugs, it is recommended to use drugs under the guidance of a doctor, not blindly self-medication to avoid adverse effects.