No amount of high glutamyl transpeptidase can confirm a diagnosis of hepatitis. Hepatitis is an inflammatory reaction in the liver caused by viral, bacterial, alcohol, and drug causes, with the possibility of abdominal pain, indigestion, nausea, and vomiting. Glutamyl transpeptidase is found mainly in the kidneys, pancreas, liver and other organs, with a normal range of 3 to 50 U/L. The reference values are not exactly the same due to different instruments. Glutamyl transpeptidase in the blood is mainly derived from hepatocyte plasma and intrahepatic bile duct epithelium. When diseases such as chronic active hepatitis, cirrhosis, alcoholic liver disease, obstructive jaundice, and hepatocellular carcinoma are present, increased destruction of hepatocytes as well as impaired excretion may lead to elevated glutamyl transpeptidase. If hepatitis is suspected to be the cause of elevated glutamyltransferase, further examination of liver and gallbladder ultrasound, hepatitis viral antibody antigen test or viral nucleic acid test is needed to clarify the diagnosis.