The latest diagnostic criteria for SLE are a combination of the patient’s antinuclear antibody titer, white blood cell count, platelet count, clinical symptoms, signs and symptoms, and other auxiliary examination results. A patient’s antinuclear antibody titer of ≥1:80 is the basic condition for diagnosis of SLE. After meeting the antibody titer criteria, the patient is then referred to additional entries for diagnostic scoring, which broadly include the presence of fever, delirium, hemolytic anemia, non-scarring alopecia, oral ulcers, and joint involvement, etc. Each entry has a different score, ranging from 2 to 5 points. The number of points obtained for each entry varies, ranging from 2 to 10, with no points awarded if the entry can be explained by other diseases more compatible with SLE than SLE, and all entries need not occur at the same time. SLE is diagnosed when the cumulative score is higher than 10 points and infections, tumors, and other autoimmune diseases are excluded. The diagnosis of SLE needs to be made by a professional doctor, and patients are recommended to visit the rheumatology and immunology department of a regular hospital for diagnosis and treatment under the guidance of a professional doctor.