Buco and Gevax are trade names, and their generic names are both Metformin Hydrochloride Extended-Release Tablets. Both have the same ingredients and uniform efficacy, and there is no such thing as which brand is better. Metformin Hydrochloride Extended-Release Tablets mainly play a role in lowering hypoglycemia, which can treat type 2 diabetes mellitus, and after taking it, you can experience adverse reactions such as vomiting, nausea, diarrhea, abdominal pain, dizziness, fatigue, myalgia, rash, low blood pressure, lactic acidosis, and so on. The drug should be swallowed whole with or after meals, not chewed. Renal function should be tested during administration and the lowest effective dose should be administered to minimize the risk of lactic acidosis. Lactic acidosis, when it occurs, can be life-threatening. The drug can interact with a number of drugs, for example, when combined with nifedipine, the drug’s own blood concentration is increased, but its excretion via the urine is also increased. When combined with tachyphylaxis, the blood concentration of tachyphylaxis decreases, while its blood concentration increases. It is contraindicated in pregnant women; previous lactic acidosis; type 2 diabetes mellitus with ketoacidosis; severe infections and trauma; hypersensitivity to the drug; hepatic and renal insufficiency; major surgery; heart failure; acute myocardial infarction; clinical hypotension and hypoxia. The drug can be secreted through breast milk, so breastfeeding should be discontinued when used by lactating women. If you need to use the drug patients, please under the guidance of the doctor strictly comply with the doctor’s instructions to take medication, do not self-medication.