Long-term application of hormone-containing ointment is harmful to the human body, mainly due to the emergence of a variety of adverse reactions, and even the formation of hormone-dependent dermatitis. 1. Adverse reactions: hormone-containing ointment, generally refers to the glucocorticoid-containing topical drugs, long time, large dose use will appear a variety of adverse reactions, such as localized skin hairiness, skin atrophy, capillary dilatation, as well as induced infections and so on. 2. Hormone-dependent dermatitis: is due to the prolonged abuse of hormone drugs, inhibit the proliferation and differentiation of epidermal cells, and destroy the skin barrier, and induce a kind of inflammatory changes, in the clinic can be manifested as thinning of the skin, redness, but also can be manifested as dryness, flaking and itching and so on. In order to ensure the safety and effectiveness of the medication, it is recommended that the use of hormone-containing ointments should always go to the hospital and be used correctly under the guidance of a doctor.