The late stage mentioned here mainly refers to the treatment of late stage diabetic patients with poor pancreatic islet function and with complications. Generally speaking, in this period, diabetic patients not only have poor pancreatic islet function, but also often have various serious chronic complications, so in addition to strict control of blood sugar, they should also actively control various cardiovascular disease risk factors, such as lowering blood pressure, regulating lipids, lowering viscosity, expanding blood vessels, improving microcirculation, etc.; secondly, they should also take corresponding treatment measures for various diabetic complications, such as laser photocoagulation for diabetic retinopathy, interventional treatment for diabetic lower limb vascular disease, etc. Interventional treatment of diabetic lower limb vasculopathy, etc. The emphasis is on comprehensive control of various cardiovascular, or peripheral vascular risk factors. Individualized treatment is an important principle that must be followed in the treatment of advanced diabetes mellitus, specifically for each diabetic patient, the length of the disease, body fat and thin, liver and kidney function, the situation of complications and the characteristics of the blood glucose spectrum, the effective development of the program, scientific and reasonable selection of drugs and dose adjustment. It is generally recommended to choose insulin therapy. Where microalbuminuria is not detected in the initial screening, it should be examined once a year thereafter. Medication, once microalbuminuria occurs, regardless of the presence of hypertension, should be taken under the guidance of a doctor angiotensin-converting enzyme inhibitor or angiotensin receptor blocker class of drugs. This diabetes treatment not only lowers blood pressure, but also reduces urinary albumin and delays the progression of kidney damage. Herbal treatment, in this time period, also has a clear effect of improving symptoms, alleviating the condition and improving symptoms, and timely intervention is recommended if the situation requires it.