The formal medical name for true red blood cells is true erythrocytosis, and it is impossible to tell how long the treatment will eliminate the symptoms for a specific period of time, and most of them are prone to relapse after stopping the medication, so they need to be controlled by long-term or even lifelong medication. Typical symptoms of true erythrocytosis include headache, dizziness, redness and purple coloring of the face, nose, ears, lips and palms, and congestion of the retina and oral mucous membranes, as well as thrombosis, embolism, hemorrhage, itching of the skin, and liver and spleen enlargement. The treatment of the disease is aimed at relieving symptoms, avoiding thrombosis, inhibiting malignant cloning, delaying or reducing the occurrence of myelofibrosis and leukemia and other long-term complications, thus improving the quality of survival and prolonging the survival period. Treatments include: venous bloodletting, thromboprophylaxis, and hypocellular therapy. Medications include hydroxyurea, aspirin, etc. If the diagnosis of true erythrocytosis is confirmed, it is recommended to consult the hospital in time, and standardized treatment under the guidance of doctors.