Phosphate is one of the common natural components in food. Abnormal intake of phosphate can cause certain effects on the human body, such as high intake of phosphate can cause hyperphosphatemia, while decreased phosphorus intake and absorption can lead to the occurrence of hypophosphatemia. Increased phosphate intake and decreased excretion can cause an increase in blood phosphate levels above the normal level and lead to hyperphosphatemia. If hyperphosphatemia persists for too long, it can affect the stability of the internal environment of calcium, leading to metastatic calcification and can inhibit calcium absorption, secondary hypocalcemia, and then symptoms such as tetany occur. Due to the reduction of phosphorus intake and absorption, excessive loss of urinary phosphorus can cause hypophosphatemia, the patient may appear nausea, vomiting, irritability, anorexia, coma, muscle pain, movement disorders and a series of clinical manifestations. Milk, lean meat and other foods are high in calcium, and their intake can be increased appropriately to regulate the ratio of calcium and phosphorus in the body. A well-balanced diet usually does not lead to disturbances in blood phosphorus metabolism in normal people.